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US Patent 12016886 Microvascular endothelial cell comprising a nucleic acid encoding an anti-TDP-43 fab

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Is a
Patent
Patent
0

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
120168860
Patent Inventor Names
Reynald Thinard0
Claude Nicolau0
Claudine Kieda0
Ruth Greferath0
Melanie Chevalier0
Date of Patent
June 25, 2024
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Patent Application Number
180467340
Date Filed
October 14, 2022
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Patent Citations
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US Patent 9304138 Pharmaceutical composition
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US Patent 9403902 Methods of treating ocular disease associated with amyloid-beta-related pathology using an anti-amyloid-beta antibody
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US Patent 9518078 Disaccharide synthetic lipid compounds and uses thereof
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US Patent 9540434 Phosphospecific antibodies recognising tau
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US Patent 9585956 Polynucleotides encoding anti-amyloid beta monoclonal antibodies
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US Patent 9598485 Anti-tau antibodies and methods of use
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Patent Primary Examiner
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Chang-Yu Wang
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CPC Code
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C12N 15/86
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C12N 5/0602
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C12N 5/0623
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C07K 16/18
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A61P 25/00
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A61P 25/28
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A61P 25/14
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A61P 21/00
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Patent abstract

The present invention relates, in part, to cell-based gene therapies, including those targeting, by way of non-limiting example, TDP43 and Aβ aggregates, for the use in neurodegenerative disorders, including without limitation Amyotrophic Lateral Sclerosis (ALS) and Alzheimer's Disease, respectively.

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