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US Patent 11999802 Compositions and methods for selective protein degradation

Patent 11999802 was granted and assigned to Novartis on June, 2024 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Novartis
Novartis
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Current Assignee
Novartis
Novartis
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
119998020
Patent Inventor Names
Jonathan M. Solomon0
James E. Bradner0
Seth Carbonneau0
Marc Horst Peter Hild0
Nathan Thomas Ross0
Carleton Proctor Goold0
Rohan Eric John Beckwith0
Carla Patricia Pinto Guimaraes0
...
Date of Patent
June 4, 2024
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Patent Application Number
167570260
Date Filed
October 18, 2018
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Patent Citations
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US Patent 7320787 Redirection of cellular immunity by protein tyrosine kinase chimeras
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US Patent 7049136 Redirection of cellular immunity by receptor chimeras
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US Patent 7052906 Synthetic transmembrane components
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US Patent 7070995 CE7-specific redirected immune cells
0
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US Patent 7265209 CE7-specific chimeric T cell receptor
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US Patent 7319143 Genetically-engineered MHC molecules
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US Patent 8911993 Compositions for treatment of cancer
0
‌
US Patent 8916381 Methods for treatment of cancer
0
...
Patent Primary Examiner
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Phuong Huynh
0
Patent abstract

The invention provides compositions including a fusion polypeptide and methods for making a fusion polypeptide that includes a COF1/CRBN-binding polypeptide, COF2/CRBN-binding polypeptide, or COF3/CRBN-binding polypeptide and a heterologous polypeptide of interest.

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