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US Patent 11840555 Methods and compositions for antibody-evading virus vectors

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Long Ping Victor Tse0

Mavis Agbandje-McKenna0

Brittney Gurda0

Aravind Asokan0

Date of Patent

December 12, 2023

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Patent Application Number

175265100

Date Filed

November 15, 2021

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Patent Citations

US Patent 7906111 Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses therefor

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US Patent 9879275 Nucleotide sequences and corresponding polypeptides conferring improved nitrogen use efficiency characteristics in plants

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US Patent 9890396 Adeno-associated virus vector variants for high efficiency genome editing and methods thereof

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US Patent 9909142 Composition and methods for highly efficient gene transfer using AAV capsid variants

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US Patent 9920097 Capsid-modified rAAV vector compositions having improved transduction efficiencies, and methods of use

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US Patent 9944908 Polypeptide

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US Patent 9976157 Isolated polynucleotides and polypeptides, and methods of using same for increasing plant yield and/or agricultural characteristics

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US Patent 10011640 Capsid-modified rAAV vector compositions and methods therefor

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Patent Primary Examiner

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CPC Code

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C12N 2750/14122

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Patent abstract

The present invention provides AAV capsid proteins comprising a modification in the amino acid sequence and virus vectors comprising the modified AAV capsid protein. The invention also provides methods of administering the virus vectors and virus capsids of the invention to a cell or to a subject in vivo.

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