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US Patent 11753476 Combination therapy for cancers with BRAF mutation

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Contents

Is a
Patent
Patent

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11753476
Patent Inventor Names
Yiyou Chen
Chun Jiang
Date of Patent
September 12, 2023
Patent Application Number
17045982
Date Filed
April 8, 2019
Patent Citations
‌
US Patent 10004735 Methods for treating cancer using TOR kinase inhibitor combination therapy comprising administering substituted pyrazino[2,3-b]pyrazines
‌
US Patent 9662329 Use of survivin antagonists in polyomavirus-related disease
‌
US Patent 9737535 Methods for treating cancer using TOR kinase inhibitor combination therapy comprising administering substituted pyrazino[2,3-b]pyrazines
‌
US Patent 7132511 Modified anti-EGFR antibodies with reduced immunogenicity
‌
US Patent 7247301 Human monoclonal antibodies to epidermal growth factor receptor (EGFR)
‌
US Patent 7595378 Human monoclonal antibodies to epidermal growth factor receptor (EGFR)
‌
US Patent 7618992 Method of treating cancer by co-administration of anticancer agents
‌
US Patent 7723484 Anti-EGFR antibodies
...
Patent Primary Examiner
‌
Sarah Pihonak
CPC Code
‌
A61K 39/3955
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A61K 39/39558
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A61K 2039/505
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A61K 2039/545
‌
A61K 2039/55
‌
A61K 31/506
‌
A61P 35/00
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C07K 16/2863
...

The present disclosure provides a combination therapy for treating cancer with BRAF mutations comprising administrating to a subject an effective amount of (a) an epidermal growth factor receptor (EGFR) inhibitor; (b) a mitogen-activated protein kinase (MEK) 1/2 inhibitor; and (c) a cyclin dependent kinase (CDK) 4/6 inhibitor. Also provided are compositions and kits related to the combination therapy.

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