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US Patent 11660340 Combination therapy using T cell redirection antigen binding molecule against cell having immunosuppressing function

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Is a
Patent
Patent
0

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
116603400
Date of Patent
May 30, 2023
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Patent Application Number
157765870
Date Filed
November 17, 2016
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Patent Citations
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US Patent 7728114 Anti-CD3 antibodies and methods of use thereof
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US Patent 8101186 Peptides that block the binding of IgG to FcRn
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US Patent 8263073 Anti-CTLA-4 antibodies with reduced blocking of binding of CTLA-4 to B7 and uses thereof
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US Patent 8398956 In vivo copper-free click chemistry for delivery of therapeutic and/or diagnostic agents
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US Patent 8586713 Readily isolated bispecific antibodies with native immunoglobulin format
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US Patent 8796424 Tri- or tetraspecific antibodies
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US Patent 8871912 Engineered heterodimeric protein domains
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US Patent 9067986 Method for making heteromultimeric molecules
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...
Patent Primary Examiner
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Lynn A Bristol
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CPC Code
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A61K 2039/507
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A61K 45/00
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A61K 39/395
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A61K 39/39558
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A61P 35/00
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A61K 31/7068
0

The present invention provides methods for treating or preventing cancer by administering an anticancer agent and an antigen-binding molecule comprising a domain that binds to a molecule expressed on the surface of a cell having an immune response-suppressing function and a T cell receptor complex-binding domain. The present invention also provides pharmaceutical compositions for treating or preventing cancer, each comprising a combination of the anticancer agent and the antigen-binding molecule.

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