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US Patent 11564929 Combination therapy with Notch and PI3K/mTOR inhibitors for use in treating cancer

Patent 11564929 was granted and assigned to Eli Lilly and Company on January, 2023 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent
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Patent attributes

Patent Applicant
Eli Lilly
Eli Lilly
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Current Assignee
Eli Lilly
Eli Lilly
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
115649290
Date of Patent
January 31, 2023
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Patent Application Number
160931170
Date Filed
April 5, 2017
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Patent Citations
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US Patent 10555951 Targeted treatment of leiomyosarcoma
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US Patent 10688104 Combination therapy with Notch and PD-1 or PD-L1 inhibitors
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US Patent 11298362 Combination therapy with Notch and CDK4/6 inhibitors for the treatment of cancer
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Patent Primary Examiner
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Sun Jae Yoo
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CPC Code
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A61P 15/08
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A61P 43/00
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A61K 31/444
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A61K 31/4745
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A61K 31/55
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A61K 2300/00
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A61P 35/02
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A61P 35/00
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Medicaments for use in treating T-cell acute lymphoblastic leukemia, acute lymphoblastic leukemia, acute myelogenous leukemia, chronic myelogenous leukemia, breast cancer, ovarian cancer, melanoma, lung cancer, pancreatic cancer, glioblastoma, sarcoma, desmoid tumors, adenoid cystic carcinoma, colorectal cancer, head and neck cancer, cervical cancer, prostate cancer, liver cancer, or skin cancer in a patient comprising combination therapy with 4,4,4-trifluoro-N-[(1S)-2-[[(7S)-5-(2-hydroxyethyl)-6-oxo-7H-pyrido[2,3-d][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]butanamide, or a pharmaceutically acceptable salt or hydrate thereof, and 8-[5-(1-hydroxy-1-methylethyl)pyridin-3-yl]-1-[(2S)-2-methoxypropyl]-3-methyl-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one, or a pharmaceutically acceptable salt thereof.

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