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US Patent 11513076 Single molecule detection or quantification using DNA nanotechnology

Patent 11513076 was granted and assigned to Ludwig-Maximilians-Universität München on November, 2022 by the United States Patent and Trademark Office.

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Is a
Patent
Patent

Patent attributes

Patent Applicant
Ludwig-Maximilians-Universität München
Ludwig-Maximilians-Universität München
Current Assignee
Ludwig-Maximilians-Universität München
Ludwig-Maximilians-Universität München
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11513076
Date of Patent
November 29, 2022
Patent Application Number
16310322
Date Filed
June 14, 2017
Patent Citations
‌
US Patent 10137426 Screening assays and methods
‌
US Patent 10018643 Systems and methods for multi-analysis
‌
US Patent 10024796 Nucleic acid nanostructure barcode probes
‌
US Patent 10041108 Methods and compositions relating to optical super-resolution patterning
‌
US Patent 10099195 Method for positioning structures in indentations and arrangements thus obtainable
‌
US Patent 10099920 Scalable nucleic acid-based nanofabrication
‌
US Patent 10534009 Systems and methods for multi-analysis
‌
US Patent 10549277 Integrated microfluidic platform for selective extraction of single-cell mRNA
...
Patent Citations Received
‌
US Patent 11866775 Methods for isothermal molecular amplification with nanoparticle-based reactions
0
Patent Primary Examiner
‌
Narayan K Bhat
CPC Code
‌
G01N 33/587
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B82Y 15/00
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B82Y 35/00
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G01N 21/6428
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C12Q 1/682
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C12Q 2525/313
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C12Q 2565/1025
‌
C07H 21/04

The present invention relates to a method and a DNA nanostructure for detecting a target structure. In particular, the present invention relates to a DNA nanostructure, which ensures a preferably linear dependence on the number of marker molecules and the measurement signal regardless of the physical arrangement of a plurality of such DNA nanostructures by virtue of the skilled selection of the shape of the DNA nanostructure and the placement of the marker molecules attached to it. The invention additionally relates to the use of said DNA nanostructures and other nanoreporters, preferably in combination with adapters which bind specifically to target molecules, in a method for quantifying a plurality of target molecules, preferably in a simultaneous manner, using a multiplex method.

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