Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yanke Liang0
Minsheng He0
Martin Duplessis0
James A. Henderson0
Christopher G. Nasveschuk0
Chi-Li Chen0
Andrew J. Phillips0
Date of Patent
October 4, 2022
0Patent Application Number
167216500
Date Filed
December 19, 2019
0Patent Citations
Patent Citations Received
Patent Primary Examiner
This invention provides Degronimers that have E3 Ubiquitin Ligase targeting moieties (Degrons) that can be linked to a targeting ligand for a protein that has been selected for in vivo degradation, and methods of use and compositions thereof as well as methods for their preparation. The invention also provides Degrons that can be used to treat disorders mediated by cereblon or an Ikaros family protein, and methods of use and compositions thereof as well as methods for their preparation.
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