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US Patent 11286255 Pyridone carboxylic acid derivative or salt thereof

Patent 11286255 was granted and assigned to Wakunaga Pharmaceutical on March, 2022 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
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Wakunaga Pharmaceutical
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Current Assignee
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Wakunaga Pharmaceutical
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
112862550
Patent Inventor Names
Yohei Kawakubo0
Kenji Itoh0
Masayuki Sato0
Rumiko Shimabara0
Taichi Ueshima0
Tatsuya Hirano0
Tomonori Yamaguchi0
Akira Yazaki0
...
Date of Patent
March 29, 2022
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Patent Application Number
164961450
Date Filed
March 23, 2018
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Patent Primary Examiner
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Taylor V Oh
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CPC Code
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C07D 471/04
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C07D 519/00
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A61P 35/00
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Patent abstract

It is intended to provide a novel compound having high antitumor activity and low toxicity to normal cells. The present invention provides a pyridone carboxylic acid derivative represented by the following formula (1) or a salt thereof wherein R1 represents a hydrogen atom, a halogen atom or the like; R2 represents a hydrogen atom, a halogen atom or the like; R3 to R6 each represent a hydrogen atom or the like; R7 represents a hydrogen atom or the like; R8 represents a hydrogen atom, a halogen atom, the following formula (a) (wherein Ra1 and Ra2 each represent a hydrogen atom, a hydroxy group, an optionally substituted lower alkyl group or the like) or the like, or R7 and R8 together represent ═N—OR10 (wherein R10 represents a hydrogen atom, an optionally substituted lower alkyl group, or an aralkyl group), or R7 and R8 form an optionally substituted 4- to 6-membered saturated hetero ring together with the adjacent carbon atom, or the like; R9 represents a hydrogen atom or the like; X represents a nitrogen atom or the like; and Y represents a nitrogen atom or the like.

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