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US Patent 11026939 High dosage valbenazine formulation and compositions, methods, and kits related thereto

Patent 11026939 was granted and assigned to Neurocrine Biosciences on June, 2021 by the United States Patent and Trademark Office.

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Is a

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Patent attributes

Patent Applicant

Neurocrine Biosciences

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Current Assignee

Neurocrine Biosciences

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Richard Alexander Moore, Jr.0

Christopher F. O{grave over ( )}Brien0

Gregory A. McClelland0

Date of Patent

June 8, 2021

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Patent Application Number

170742780

Date Filed

October 19, 2020

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Patent Citations

US Patent 10160757 Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl 2-amino-3-methylbutanoate di(4-methylbenzenesulfonate)

US Patent 10065952 Valbenazine salts and polymorphs thereof

US Patent 10689380 Crystalline forms of valbenazine ditosylate

Patent Citations Received

US Patent 11439629 Methods for the administration of certain VMAT2 inhibitors

US Patent 11654142 Methods for the administration of certain VMAT2 inhibitors

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US Patent 11311532 High dosage valbenazine formulation and compositions, methods, and kits related thereto

Patent Primary Examiner

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Patent abstract

Solid pharmaceutical compositions with high drug loading are provided. A formulation useful for the solid pharmaceutical composition includes valbenazine, or a pharmaceutically acceptable salt thereof, silicified microcrystalline cellulose, isomalt, hydroxypropyl methylcellulose, partially pregelatinized maize starch, and magnesium stearate.

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