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US Patent 10421804 Anti-Zika virus antibodies and methods of use

Patent 10421804 was granted and assigned to Regeneron Pharmaceuticals on September, 2019 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent

Patent attributes

Patent Applicant
Regeneron Pharmaceuticals
Regeneron Pharmaceuticals
Current Assignee
Regeneron Pharmaceuticals
Regeneron Pharmaceuticals
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10421804
Date of Patent
September 24, 2019
Patent Application Number
15651387
Date Filed
July 17, 2017
Patent Citations Received
‌
US Patent 11926658 Multispecific antibodies specifically binding to Zika virus epitopes
0
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US Patent 11780908 Anti-dengue virus antibodies, polypeptides containing variant FC regions, and methods of use
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US Patent 11891432 Anti-dengue virus antibodies having cross-reactivity to Zika virus and methods of use
0
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US Patent 11912757 Antibodies specifically binding to Zika virus epitopes and uses thereof
0
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US Patent 11590223 Dosing strategy that mitigates cytokine release syndrome for therapeutic antibodies
Patent Primary Examiner
‌
Stacy B. Chen
Patent abstract

The present invention provides monoclonal antibodies, or antigen-binding fragments thereof, that bind to ZIKV glycoproteins, pharmaceutical compositions comprising the antibodies and methods of use. The antibodies of the invention are useful for inhibiting or neutralizing ZIKV activity, thus providing a means of treating or preventing ZIKV infection in humans. In some embodiments, the invention provides for use of one or more antibodies that bind to the ZIKV for preventing viral attachment and/or entry into host cells. The antibodies of the invention may be used prophylactically or therapeutically and may be used alone or in combination with one or more other anti-viral agents or vaccines.

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