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Synthace

Synthace

Synthace is a software company based out of London, UK building automation software that gives biologists the ability to control and analyze the performance of lab hardware.

Synthace is a software company, founded in 2011 by Sean Ward, Markus Gershater, and Christopher Grant. Synthace builds software tools that work with scientists and their lab hardware with the goal of improving lab productivity. Their software allows scientists to communicate with their lab hardware in a way that lets them plan, execute, and repeat biological experiments.

Products and services

Antha

Antha is an open source language and cloud based operating platform made by Synthace. Antha is made to help scientists design, execute, analyze, and replicate aspects of their lab work. The company claims that Antha can produce a 100-fold improvement in lab productivity, a 50% reduction in the time it takes to generate internal vector constructions, a 33% reduction in the cost of running experiments, and increase enzymatic activity by 100X compared to pre-Antha platforms. Below you can find brief descriptions of specific services Antha software offers to users which are: construct assembly, data integration, and liquid handling.

Antha helps scientists build type IIS construct assemblies by automating and reproducing the workflow of lab hardware involved in construct assembly. This automation is made possible through the use of liquid handling robots than can perform lab tasks involved in construct assembly. Antha software allows work flows of different lab hardware systems to work together such as construct assembly, transformation, and plating-out. These process can be automated, reproduced, and customized to the needs of each laboratory. Antha software keeps track of, and organizes, information generated by lab hardware, producing clean data sets for scientists to work with, and offers online and offline visualization tools that can be easily shared with other users. Antha software is integrated with: Azure, GitHub, Python, Jupyter, Pandas, matplotlib, numpy, and jmp.

Funding

Seed round 1

On April 12th, 2013 Synthace raised $900,000 in funding from Sharaf Yamani, Sami Mikati, Michail Eleftheriou, John Anthony Knight, and David Lucas.

Seed round 2

Synthace raised $2,000,000 in seed funding on September 24th, 2013. Investors include Sofinnova Partners, Innovative UK, and Keith Willey.

Seed round 3

On December 14th, 2014 Synthace announced that it raised $3,500,000 in seed funding from Sofinnova Partners, SOSventures, Bioeconomy Capital, and the Rainbow Seed Fund.

Series A

Synthace completed its series A funding round on Septmber 19th, 2017. They received $9,600,000 in funding from White Cloud Capital, Sofinnova Partners, SOSventures, Bioeconomy Capital, Amadeus Capital, and 11.2 Capital.

Partnerships

Cambridge Consultants

In April 2017, a Synthace announced a partnership with Cambridge Consultants. The partnership is focused on promoting the adoption and improvement of Synthace's Antha software. Cambridge Consultants is offering a consulting service to help companies get the most out of Antha by helping implement features of Antha in their labs such as; process development, protocol development, custom equipment development, and automation integration. The partnership is focused on promoting the adoption and improvement of Synthace's Antha software. Cambridge Consultants is offering a consulting service to help companies get the most out of Antha by helping implement features of Antha in their labs such as; process development, protocol development, custom equipment development, and automation integration.

Dow AgroSciences LLC

Dow AgroSciences, a subsidiary of the Dow Chemical Company, announced it will begin collaborating with Synthace in October, 2015. The partnership is a research collaboration effort between the two companies to improve crop protection. Dow AgroSciences will be using Antha with their own fermentation technology to develop new microbial strains capable of producing desired chemicals. By using Antha, Dow ArgoSciences hopes to develop new products faster and cheaper for farmers that will help prevent pest infestation and control disease in ways that increase crop yields.

Gilson

Gilson and Synthace anounced their partnership in April, 2018. The companies pledged to begin working together to merge Antha with Gilson's liquid handling platform PIPETMAX. They are workign on creating a visual drag and drop system that will allow the people using PIPETMAX to customize their workflows. The software system will be able to be used remotely for programming many tasks of the PIPETMAX such as: transfers, dilutions, master mix preparation, and provide data management.

Merck & Co

In November 2015, Merck and Synthace announced they will be working together to optimize their Antha software to become a better bio-manufacturing platform. Synthace is hoping to use the large amount of experience Merck has manufacturing pharmaceuticals to improve the functionality of their Antha software.

Microsoft

On April 6th, 2016 a partnership was announced between Microsoft and Synthace. The partnership is through Microsofts BizSpark Plus program, and gives Synthace the ability to use the Azure cloud analytics, cognitive services, and machine learning capabilities of Microsoft to improve Antha and Synthace. The partnership is through Microsofts BizSpark Plus program, and gives Synthace the ability to use the Azure cloud analytics, cognitive services, and machine learning capabilities of Microsoft to improve Antha.

Oxford Biomedica, Cell and Gene Therapy Catapult, and Stratophase

Oxford Biomedica is the lead partner in this partnership between Synthace, Cell and Gene Therapy Catapult, and Stratophase. The partnerships between these companies was announced in August, 2017 and is focused on developing more efficient cell and gene manufacturing systems and technologies.

Patents

Patent description
Inventors
Status
Date
App/pub number

Michael Ian Sadowski, Sean Michael Ward

Application

2017-01-12

US20170011170A1

Markus Christian Gershater, Sean Michael Ward, Michael Ian Sadowski, Christopher Richard Grant

Application

2017-01-12

US20170011045A1

Timeline

Series A Funding Round

Synthace completed its series A funding round on Septmber 19th, 2017. They received $9,600,000 in funding from White Cloud Capital, Sofinnova Partners, SOSventures, Bioeconomy Capital, Amadeus Capital, and 11.2 Capital.

Partnership: Oxford Biomedica, Cell and Gene Therapy Catapult, and Stratophase

Oxford Biomedica is the lead partner in this partnership between Synthace, Cell and Gene Therapy Catapult, and Stratophase. The partnerships between these companies was announced in August, 2017 and is focused on developing more efficient cell and gene manufacturing systems and technologies.

Partnership: Cambridge Consultants

In April 2017, a Synthace announced a partnership with Cambridge Analytica. The partnership is focused on promoting the adoption and improvement of Synthace's Antha software. Cambridge Analytica is offering a consulting service to help companies get the most out of Antha by helping implement features of Antha in their labs such as; process development, protocol development, custom equipment development, and automation integration.

Partnership: Microsoft

On April 6th, 2016 a partnership was announced between Microsoft and Synthace. The partnership is through Microsofts BizSpark Plus program, and gives Synthace the ability to use the Azure cloud analytics, cognitive services, and machine learning capabilities of Microsoft to improve Antha.

Partnership: Merck & Co

In November 2015, Merck and Synthace announced they will be working together to optimize their Antha software to become a better bio-manufacturing platform. Synthace is hoping to use the large amount of experience Merck has manufacturing pharmaceuticals to improve the functionality of their Antha software.

Partnership: Dow AgroSciences LLC

Dow AgroSciences is a subsidiary of the Dow Chemical Company that announced it will begin collaborating with Synthace in October, 2015. The partnership is a research collaboration effort between the two companies to improve crop protection. Dow AgroSciences will be using Antha with their own fermentation technology to develop new microbial strains capable of producing desired chemicals. By using Antha, Dow ArgoSciences hopes to develop new products faster and cheaper for farmers that will help prevent pest infestation and control disease in ways that increase crop yields.

Seed Funding Round 3

On December 14th, 2014 Synthace announced that it raised $3,500,000 in seed funding from Sofinnova Partners, SOSventures, Bioeconomy Capital, and the Rainbow Seed Fund.

Seed Funding Round 2

Synthace raised $2,000,000 in seed funding on September 24th, 2013. Investors include Sofinnova Partners, Innovative UK, and Keith Willey.

Seed Funding Round 1

On April 12th, 2013 Synthace raised $900,000 in funding from Sharaf Yamani, Sami Mikati, Michail Eleftheriou, John Anthony Knight, and David Lucas.

People

Name
Role
Related Golden topics

Bill Liao

Non-Executive Director

Christopher Grant

Founder

Isabel Fox

Non-executive Director

Josko Bobanovic

Non-executive Director

Mark Watson

Chief Commercial Officer

Markus Gershater

Chief Scientific Officer

Michael Sadowski

Head of Bioinformatics

Sean Ward

Chief Technology Officer

Tim Fell

Chief Executive Officer

Further reading

Author
Title
Link
Type

Akash Anand

Universal ”Nanobots Market” Booming at ~21% CAGR in Asia Specific Region | Emerging Technologies | Competitive Landscape and Future Forecasts up to 2023

Daniela Quaglia

​Antha: a platform for engineering biology

Evan Appleton, Douglas Densmore, Curtis Madsen, Nicholas Roehner

Needs and opportunities in bio-design automation: four areas for focus

Academic paper

Github

The Official Antha Language Repositories

GitHub repository

Jacop Beal, Aaron Adler, Fusun Yaman

Managing bioengineering complexity with AI techniques

Academic paper

James Scott-Brown, Antonis Papachristodoulou

Visual Representation of Experimental Protocols

Academic paper

Mike Butcher

Synthace raises a £7.3m Series A to bring open source to biotech

Raphael Ferreira

Taking Biotech to the Next Level - How about Automation? - Labiotech.eu

Steven Burgess

SynBio is Booming | PLOS Synthetic Biology Community

Synthace

Antha OS Documentation

Thomas Craig, Richard Holland, Rosalinda D’Amore, James Johnson, Hannah V McCue, Anthony West, Valentin Zulkower, Hille Tekotte, Yizhi Cai, Daniel Swan, Robert P Davey, Christiane Hertz-Fowler, Anthony Hall, Mark Caddick

Leaf LIMS: A flexible laboratory information management system with a synthetic biology focus

Academic paper

Documentaries, videos and podcasts

Title
Date
Link

Dr. Xander Anderson on Antha (RebelBioFuture)

March 16, 2017

How synthetic biology is exploring biological complexity: Sean Ward at TEDxVilnius

February 25, 2014

SynBio Talks: Introducing Synthace - a synthetic biology startup, by Sean Ward

December 10, 2012

Technology Pioneer 2016 - Tim Fell (Synthace)

June 27, 2016

Companies

Company
CEO
Location
Products/Services

References