Sr One

Sr One

A venture capital and private equity firm investing in biotechnology companies.

Sr One is a venture capital and private equity firm investing in biotechnology companies that is headquartered in Cambridge, Massachusetts and was founded in 1985 as the sub-organization of GlaxoSmithKline. Sr One has invested over $830 million invested in the biotechnology space.

Investments

Sr One invests in pre-clinical, clinical, and commercial stage biotechnology companies. Notable investments made by Sr One include: Atopix, Alios BioPharma, NuPathe, Concert Pharmaceuticals, Gotham Therapeutics, Illuminoss, TP Therapeutics, ProtAffin, CRISPR Therapeutics, Arcellx, Adheron Therapeutics, Pulmocide, Second Genome, Sumprus Biosciences, Propeller, VHsquared, Nimbus Therapeutics, AGTC, and Constellation Pharmaceuticals.

Their exited investments include CRISPR Therapeutics, Progyny, Propeller Health, Genocea Biosciences, Bicycle Therapeutics, Dicerna Pharmaceuticals, Turning Point Therapeutics, ZappRx, Morphic Therapeutic, Translate Bio and Spero Therapeutics.

Timeline

Funded Companies

Company
Description
Industry
Website
Location
Genocea Biosciences

A biopharmaceutical company developing T cell vaccines and immunotherapies

Biotechnology
Cambridge, Massachusetts
Nkarta Therapeutics

Nkarta Therapeutics is a biotechnology company using natural killer (NK) immune cells for cellular therapies.

Biotechnology
South San Francisco, California
Gotham Therapeutics

A biotechnology company discovering drugs that target the epitranscriptomics machinery that modifies RNA.

Biotechnology
New York City
MISSION Therapeutics

MISSION Therapeutics is a Cambridge, Cambridgeshire-based biotechnology company offering a platform for the development of small molecule drugs that selectively target deubiquitylating enzymes.

Biotechnology
Cambridge, Cambridgeshire
Constellation Pharmaceuticals

A biopharmaceutical company dedicated to the development of novel therapeutics in the field of Epigenetics

Biotechnology
Cambridge, Massachusetts
Pandion Therapeutics

Pandion Therapeutics is a Cambridge, Massachusetts-based company developing modular proteins, antibodies and bispecifics for autoimmune and inflammatory diseases.

Biotechnology
Cambridge, Massachusetts
Propeller Health

Propeller Health is a Madison, Wisconsin-based company offering sensors, mobile apps, analytics and services to support respiratory health management.

Software engineering
Madison, Wisconsin
Effector Therapeutics

A company dedicated on the discovery and development of small molecule therapeutics to treat cancer

Biotechnology
San Diego
Alios Biopharma

A biotechnology company developing medicines to treatment viral diseases

Biotechnology
South San Francisco, California
Principia BioPharma

A biopharmaceutical company developing oral small molecule therapies for the treatment of cancer and autoimmune diseases

Biotechnology
South San Francisco, California
Decibel Therapeutics

Decibel Therapeutics is a Boston-based company founded in 2015 by Gabriel Corfas.

Drug discovery
Boston
ZappRx

ZappRx is a Cambridge, Massachusetts-based health information technology company founded in 2012.

Health information technology
Cambridge, Massachusetts
Palleon Pharmaceuticals

Palleon Pharmaceuticals is a Waltham, Massachusetts-based company.

Waltham, Massachusetts
Bicycle Therapeutics

Biotechnology
Cambridge, Massachusetts
PsiOxus Therapeutics

PsiOxus Therapeutics is an Oxfordshire-based company founded in 2006 by Kerry Fisher.

Biotechnology
Oxfordshire
IlluminOss Medical

IlluminOss Medical is a East Providence, Rhode Island-based healthcare company founded by Arnold Peter Weiss.

Healthcare
East Providence, Rhode Island
Applied Genetic Technologies Corporation

Applied Genetic Technologies Corporation is an Alachua, Florida-based company.

Alachua, Florida
Pulmocide

Pulmocide is a London-based company.

London
Macrolide Pharmaceuticals

Macrolide Pharmaceuticals is a Watertown, Massachusetts-based company.

Watertown, Massachusetts
Auxogyn

Company

TP Therapeutics

TP Therapeutics is a San Diego-based company.

San Diego
F-star Alpha

Onyvax

River Vision Development

Company

RuiYi

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People

Name
Role
LinkedIn

David Madden

Advisor

Imogen Mansfield

Employee

Jens Eckstein

Employee

Joyce A Lonergan

Employee

Rehan Mirza

Employee

Further reading

Title
Author
Link
Type
Date

Documentaries, videos and podcasts

Title
Date
Link

Companies

Company
CEO
Location
Products/Services

References

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