Sr One is a venture capital and private equity firm investing in biotechnology companies that is headquartered in Cambridge, Massachusetts and was founded in 1985 as the sub-organization of GlaxoSmithKline. Sr One has invested over $830 million invested in the biotechnology space.
Sr One invests in pre-clinical, clinical, and commercial stage biotechnology companies. Notable investments made by Sr One include: Atopix, Alios BioPharma, NuPathe, Concert Pharmaceuticals, Gotham Therapeutics, Illuminoss, TP Therapeutics, ProtAffin, CRISPR Therapeutics, Arcellx, Adheron Therapeutics, Pulmocide, Second Genome, Sumprus Biosciences, Propeller, VHsquared, Nimbus Therapeutics, AGTC, and Constellation Pharmaceuticals.
Their exited investments include CRISPR Therapeutics, Progyny, Propeller Health, Genocea Biosciences, Bicycle Therapeutics, Dicerna Pharmaceuticals, Turning Point Therapeutics, ZappRx, Morphic Therapeutic, Translate Bio and Spero Therapeutics.
Timeline
Funded Companies
A biopharmaceutical and gene editing company founded in 2013. CRISPR Therapeutics AG is based in Zug, Switzerland and CRISPR Therapeutics, Inc. is the U.S. subsidiary with R&D operations in Cambridge, Massachusetts and business offices in London, U.K.
Decibel Therapeutics conducts inner ear research to deliver medicines for hearing and balance.
A biopharmaceutical company developing T cell vaccines and immunotherapies
A clinical-stage mRNA therapeutics company developing medicines to treat diseases caused by protein or gene dysfunction and vaccines against infectious disease pathogens
Nkarta Therapeutics is a biotechnology company using natural killer (NK) immune cells for cellular therapies.
Pandion Therapeutics is a Cambridge, Massachusetts-based company developing modular proteins, antibodies and bispecifics for autoimmune and inflammatory diseases.
MISSION Therapeutics is a Cambridge, Cambridgeshire-based biotechnology company offering a platform for the development of small molecule drugs that selectively target deubiquitylating enzymes.
A biotechnology company discovering drugs that target the epitranscriptomics machinery that modifies RNA.
Second Genome is a company that is developing microbiome modulators for infection, immunity and metabolic diseases.
A biopharmaceutical company dedicated to the development of novel therapeutics in the field of Epigenetics
Turning Point Therapeutics, Inc. is a clinical-stage drug design company that specializes in the discovery and development of targeted cancer therapies
Avantium Technologies is an Amsterdam-based manufacturing company offering research and development for products and applications in the energy, chemicals, and pharmaceuticals industry.
Spring Bank Pharmaceuticals, Inc. is a company founded in 2002
Hypnion was acquired by Eli Lilly and Company.
Protein Forest is a company that develops instruments, consumables and software products for proteomic analysis and biomarker discovery
Puridify is a biotechnology company that uses nanofibre technology to develop purification solutions for biotherapeutic manufacturing.
Propeller Health is a Madison, Wisconsin-based company offering sensors, mobile apps, analytics and services to support respiratory health management.
A biopharmaceutical company developing oral small molecule therapies for the treatment of cancer and autoimmune diseases
F-star is a Cambridge, Cambridgeshire-based company founded in 2006.
A company dedicated on the discovery and development of small molecule therapeutics to treat cancer
A biotechnology company developing medicines to treatment viral diseases
ZappRx is a Cambridge, Massachusetts-based health information technology company founded in 2012.
Palleon Pharmaceuticals is a Waltham, Massachusetts-based company.
Applied Genetic Technologies Corporation is an Alachua, Florida-based biotechnology company founded in 2001.
People
David Madden
Advisor
Imogen Mansfield
Employee
Jens Eckstein
Employee
Joyce A Lonergan
Employee
Rehan Mirza
Employee
