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Refeyn

Refeyn

Company developing mass photometry instrumentation that analyses biomolecules with light scattering.

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Golden AI
Golden AI edited on 12 Nov 2019 5:37 pm
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Edits on 18 May 2019
Jude Gomila"should be cross linked to uni of oxford"
Jude Gomila edited on 18 May 2019 12:46 am
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Refeyn spun out of the Chemistry Department at UniversityUniversity of Oxford to commercialize technology applied to molecular mass measurement. The company is developing scientific instrumentation called ‘mass photometry’ that uses single molecule light scattering for detection, imaging and accurate mass determination of biomolecules in solution. The technology has applications in the biopharma sector with the potential to increase productivity in protein research projects. Specific applications include mass measurement in solution, assembly and stoichiometry of protein complexes, mass measurement of heterogenous biomolecules and protein-protein interactions. Measurements are done in minutes with microliter quantities of sample. Refeyn has a table-top instrument called the Refeyn One which uses their proprietary software to automatically control the acquisition of data by performing mass analysis.

Edits on 17 May 2019
Craig Clarke
Craig Clarke approved a suggestion from Golden's AI on 17 May 2019 5:36 pm
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Refeyn is supported by Oxford Sciences Innovation (OSI). Their venture round was funded by Oxford University Innovation. In March 2019, Foresight GroupForesight Group LLP and Williams Advanced Engineering announced a £1 million equity investment into Refeyn Ltd .

Elliot Page
Elliot Page approved a suggestion from Golden's AI on 17 May 2019 3:44 pm
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Refeyn spun out of the Chemistry Department at University of Oxford to commercialize technology applied to molecular massmolecular mass measurement. The company is developing scientific instrumentation called ‘mass photometry’ that uses single molecule light scattering for detection, imaging and accurate mass determination of biomolecules in solution. The technology has applications in the biopharma sector with the potential to increase productivity in protein research projects. Specific applications include mass measurement in solution, assembly and stoichiometry of protein complexes, mass measurement of heterogenous biomolecules and protein-protein interactions. Measurements are done in minutes with microliter quantities of sample. Refeyn has a table-top instrument called the Refeyn One which uses their proprietary software to automatically control the acquisition of data by performing mass analysis.

Elliot Page
Elliot Page approved a suggestion from Golden's AI on 17 May 2019 1:24 pm
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Refeyn spun out of the Chemistry Department at University of OxfordOxford to commercialize technology applied to molecular mass measurement. The company is developing scientific instrumentation called ‘mass photometry’ that uses single molecule light scattering for detection, imaging and accurate mass determination of biomolecules in solution. The technology has applications in the biopharma sector with the potential to increase productivity in protein research projects. Specific applications include mass measurement in solution, assembly and stoichiometry of protein complexes, mass measurement of heterogenous biomolecules and protein-protein interactions. Measurements are done in minutes with microliter quantities of sample. Refeyn has a table-top instrument called the Refeyn One which uses their proprietary software to automatically control the acquisition of data by performing mass analysis.

Elliot Page
Elliot Page approved a suggestion from Golden's AI on 17 May 2019 1:24 pm
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Refeyn spun out of the Chemistry Department at UniversityUniversity of Oxford to commercialize technology applied to molecular mass measurement. The company is developing scientific instrumentation called ‘mass photometry’ that uses single molecule light scattering for detection, imaging and accurate mass determination of biomolecules in solution. The technology has applications in the biopharma sector with the potential to increase productivity in protein research projects. Specific applications include mass measurement in solution, assembly and stoichiometry of protein complexes, mass measurement of heterogenous biomolecules and protein-protein interactions. Measurements are done in minutes with microliter quantities of sample. Refeyn has a table-top instrument called the Refeyn One which uses their proprietary software to automatically control the acquisition of data by performing mass analysis.

Julius John Villarisco"Approved suggestion from source: https://www.refeyn.com/"
Julius John Villarisco approved a suggestion from Golden's AI on 17 May 2019 12:10 am
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Julius John Villarisco"Approved suggestion from source: https://www.refeyn.com/"
Julius John Villarisco approved a suggestion from Golden's AI on 16 May 2019 11:55 pm
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Edits on 16 May 2019
Meredith Hanel
Meredith Hanel edited on 16 May 2019 2:49 pm
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Meredith Hanel
Meredith Hanel edited on 16 May 2019 2:47 pm
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Refeyn

Company developing mass photometry instrumentation that analyses biomolecules with light scattering.

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Technology

...

Funding

Meredith Hanel
Meredith Hanel edited on 16 May 2019 2:43 pm
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Article

Refeyn spun out of the Chemistry Department at University of Oxford to commercialize technology applied to molecular mass measurement. The company is developing scientific instrumentation called ‘mass photometry’ that uses single molecule light scattering for detection, imaging and accurate mass determination of biomolecules in solution. The technology has applications in the biopharma sector with the potential to increase productivity in protein research projects. Specific applications include mass measurement in solution, assembly and stoichiometry of protein complexes, mass measurement of heterogenous biomolecules and protein-protein interactions. Measurements are done in minutes with microliter quantities of sample. Refeyn has a table-top instrument called the Refeyn One which uses their proprietary software to automatically control the acquisition of data by performing mass analysis.

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Mass photometry uses the principles of interference reflection microscopy and interferometric scattering microscopy. Professor Kukura and his research group used carefully controlled illumination and a novel spatial-filtering detection strategy to demonstrate that light scattered by single proteins can be detected and quantified, which was published in Science in 2018. The scattered light scales with particle volume and refractive index and the scattering signal is directly proportional to the molecular mass. Mass photometry measurements are accurate over a large mass range and can be used for glycoproteins, nucleic acids and heterogenous assemblies such as lipid nanodiscs.



Refeyn is supported by Oxford Sciences Innovation (OSI). Their venture round was funded by Oxford University Innovation. In March 2019, Foresight Group LLP and Williams Advanced Engineering announced a £1 million equity investment into Refeyn Ltd .

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Role
Related Golden topics

Andrew Bloxam

Non Executive Director



David Howells

Non Executive Director



Gabriella Kiss PhD

Product Marketing Manager and Business Development



Maria Trapatseli

Operations Engineer



Prof. Philipp Kukura

Founder and Director



Meredith Hanel
Meredith Hanel edited on 16 May 2019 2:20 pm
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Topic thumbnail

Refeyn

Company developing mass photometry instrumentation that analyses biomolecules with light scattering.

Article

Refeyn spun out of the Chemistry Department at University of Oxford to commercialize technology applied to molecular mass measurement. The company is developing scientific instrumentation called ‘mass photometry’ that uses single molecule light scattering for detection, imaging and accurate mass determination of biomolecules in solution. The technology has applications in the biopharma sector with the potential to increase productivity in protein research projects. Specific applications include mass measurement in solution, assembly and stoichiometry of protein complexes, mass measurement of heterogenous biomolecules and protein-protein interactions. Measurements are done in minutes with microliter quantities of sample.



In March 2019, Foresight Group LLP and Williams Advanced Engineering announced a £1 million equity investment into Refeyn Ltd .

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Meredith Hanel"Initial topic creation"
Meredith Hanel created this topic on 16 May 2019 1:52 pm
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 Refeyn

Company developing mass photometry instrumentation that analyses biomolecules with light scattering.

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