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Poseida Therapeutics

Poseida Therapeutics

Poseida Therapeutics develops targeted cell therapy founded in 2014 by Eric Ostertag.

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All edits by  Sameeha Sulaiman 

Edits on 15 Feb, 2019
Sameeha Sulaiman profile picture
Sameeha Sulaiman
edited on 15 Feb, 2019
Edits made to:
Article (+996/-6 characters)
Table (+1 rows) (+3 cells) (+184 characters)
Article

Poseida's leading product candidate is P-BCMA-101, an autologous CAR-T product that targets B cell maturation antigen, or BCMA, which is expressed on multiple myeloma cells. In December 2018, the compaycompany announced positive results from its first cohort of ongoing Phase 1 clinical trial. Poseida's second autologous product is P-PSMA-101, targeting cells that express prostate-specific membrane antigen, which is expressed on most prostate cancer cells. The product is being developed to treat patients with castrate-resistance prostate cancer, or CRPC, a solid tumor indication, with Phase 1 clinical trials planned in the second half of 2019.

Under the allogenic category, Poseida has P-BCMA-ALL01 and P-MUC1C-101. Derived from healthy donors, P-BCMA-ALL01 is designed to have the same inherent properties and functions of P-BCMA-101, but with the benefits of scale and administration efficiency that come from an allogenic product. The company plans to file an IND and begin Phase 1 clinical trials by late 2019 or early 2020. As for P-MUC1C-101, the product is in late-stage pre-clinical development for multiple solid tumor indications with plans for Phase 1 clinical trials in 2020.

In January 2019, Poseida Therapeutics filed documents for an IPO of $115 million.

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Xconomy: Poseida Therapeutics Prepares for IPO to Advance CAR-T Treatments

https://xconomy.com/san-diego/2019/01/04/poseida-therapeutics-prepares-for-ipo-to-advance-car-t-treatments/

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Sameeha Sulaiman profile picture
Sameeha Sulaiman
edited on 15 Feb, 2019
Edits made to:
Infobox (+3/-1 properties)
Article (+704/-227 characters)
Table (+11 rows) (+22 cells) (+467 characters)
Table (+1 rows) (+4 cells) (+396 characters)
Article

Poseida's CAR T cell therapy is genetically engineered immune cells that hone in on a cellular target present on the cancer cells, but not on any essential cells.

Poseida Therapeutics is a privately held, biopharmaceutical company based in San Diego California. It leverages proprietary non-viral, gene engineering technologies to create therapeutics for illnesses with high unmet medical needs. The company is developing a wholly-owned pipeline of autologous and allogenic CAR-T product candidates, initially focused on the treatment of hematological malignancies and other solid tumors.

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On April 3, 2018, Poseida announced $30.5m in series B funding.

Poseida's leading product candidate is P-BCMA-101, an autologous CAR-T product that targets B cell maturation antigen, or BCMA, which is expressed on multiple myeloma cells. In December 2018, the compay announced positive from its first cohort of ongoing Phase 1 clinical trial.

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Debra Gessner

VP, Regulatory Affairs

Devon J. Shedlock

VP, Preclinical Development

Glenn Dourado

VP, Business Development

Jeff Knight

VP, Clinical Development Operations and Project Management

Jennifer Collins

VP, Quality Operations

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Poseida Therapeutics Provides Update on Phase 1 Study of P-BCMA-101 CAR-T Product Candidate at the 2018 American Society of Hematology Annual Meeting

Poseida Therapeutics, Inc.

https://globenewswire.com/news-release/2018/12/04/1661326/0/en/Poseida-Therapeutics-Provides-Update-on-Phase-1-Study-of-P-BCMA-101-CAR-T-Product-Candidate-at-the-2018-American-Society-of-Hematology-Annual-Meeting.html

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Infobox
Website
https://poseida.com/
Website
https://poseida.com/
LinkedIn
https://www.linkedin.com/company/poseida-therapeutics-inc-
Twitter
https://twitter.com/poseidathera?lang=en

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