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Perelman School of Medicine at the University of Pennsylvania

Perelman School of Medicine at the University of Pennsylvania

Medical school in philadelphia, pennsylvania, united states

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May 1, 2019
WebWire
Cleft lip and palate (CL/P) is the second most common birth defect in the world, affecting 1 in 700 live born babies. While the exact cause of CL/P is not well understood, investigators think it could be the result of a combination of genetics and environment. Cleft lip and palate are splits in the upper lip, the roof of the mouth, or both. This happens when cells in a baby's face and mouth don't fuse properly during early development. The result of a partial fusion, or no fusion at all, l...
April 9, 2019
WebWire
A study lead by Penn Medicine researchers found that childhood trauma is linked to abnormal connectivity in the brain in adults with major depressive disorder (MDD). The paper, published this week in Proceedings of the National Academy of Sciences (PNAS), is the first data-driven study to show symptom-specific, system-level changes in brain network connectivity in MDD. "With estimates of approximately 10 percent of all children in the United States having been subjected to child abuse,...