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Optogenetics

Optogenetics

Neuromodulation method; uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue

Light-sensitive proteins, such as channelrhodopsin-2 (ChR-2), can serve as light-gated ion channels. When transfected into neurons, these proteins allow for optical control of the polarization of the neuron's cell membrane. For instance, neurons expressing ChR-2 will depolarize when exposed to blue light.

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