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Nuclera Nucleics

Nuclera Nucleics

Nuclera Nucleics is a Cambridge, UK based DNA synthesis biotechnology company

Nuclera is a DNA synthesis company working on the synthesis of long DNA strands. Nuclera's water-based DNA synthesis and automation platform is based on engineered terminal deoxynucleotidyl transferases (TdT) to enable the production of gene and genome libraries. Their TdT enzymes incorporate reversibly terminating nucleotide triphosphates of the four nucleobases. Nuclera aims to provide long-length (longer than 500 nucleotides) variant DNA and genome libraries for protein, biological pathway, and genome-scale engineering.

Patents

Description
Status
Link
Date

The use of specific terminal deoxynucleotidyl transferase (TdT) enzymes in a method of nucleic acid synthesis, to methods of synthesizing nucleic acids, and to the use of kits comprising said enzymes in a method of nucleic acid synthesis.

Pending

2/10/2016

A process for the preparation of nucleic acid by means of 3'-o-azidomethyl nucleotide triphosphate

Pending

9/9/2016

Azidomethyl ether deprotection method

Pending

1/19/2017

The use of a DNA polymerise theta (PolQ) enzyme in a method of template-independent nucleic acid synthesis.

Pending

7/29/2016

Timeline

People

Name
Role
Related Golden topics

Gordon McInroy

Co-founder and CSO

Jiahao Huang

Co-founder and CCO

Michael Chen

Co-founder and CTO

Further reading

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Documentaries, videos and podcasts

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Companies

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References