Nextbiotics combines bacteriophage therapy (Phage therapy) with CRISPR technology to reverse antibiotic resistance.The engineered viruses will specifically target drug-resistant bacteria and generate double-strand breaks, destroying the drug resistant genes or the genomic DNA of the bacteria, which will kill the bacteria.
Angie Carrillo Reluz
Documentaries, videos and podcasts
Global Solutions Program: NextBiotics | Maricel Saenz | SU Global Summit
- CRISPRClustered regularly interspaced short palindromic repeats (CRISPR) is a prokaryotic adaptive immune response that provides immunity against foreign nucleic acids, such as viral DNA and bacterial plasmids, through the use of crRNAs (CRISPR RNAs) and associated Cas genes.
- CRISPR/Cas ToolsClustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR associated (Cas) proteins perform adaptive immune functions in prokaryotic organisms defending against foreign nucleic acids such as viruses. CRISPR/Cas tools have been adapted for use in genome editing and other DNA and RNA targeting applications.