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Indee Labs

Indee Labs

Indee Labs focuses on the development of microfluidic vortex shedding for rapidly and efficiently transfecting human primary immune cells with negligible perturbation. The team is focused on developing its core technology for short turnaround chimeric antigen receptor T cell (CAR-T) development and manufacturing.

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Edits on 8 Nov, 2022
Amy Tomlinson Gayle
Amy Tomlinson Gayle edited on 8 Nov, 2022
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Article

Indee Labs was founded in August 2015 with a 'mission"mission to democratize gene-modified cell therapies'," such as chimeric antigen receptor T cells (CAR-T). The team is developing a novel transfection technology that can rapidly and efficiently deliver a variety of genetic material (e.g., DNA, RNA, protein, and/or various complexes) to human primary immune cells in seconds.

Microfluidic Vortexvortex Sheddingshedding

The core technology, microfluidic vortex shedding (μVS), uses a microscopic fluid dynamics phenomenon based on vortex shedding to hydrodynamically porate the cell membrane, allowing for the deliberate introduction of genetic material to human primary immune cells. Vortex shedding is not a new phenomenon. It can be observed as water flows past boulders in rivers while also being seen as clouds drift over mountains.

...

μVS is not the only transfection technology,; however, it is shown to be able to rapidly deliver a range of genetic material to human primary immune cells with high cell recovery, high cell viability and, high efficiency, and high throughput. Furthermore, μVS results in negligible perturbation of immune cell proliferation, activation, exhaustion, phenotype, function, norand transcriptome-wide gene expression. μVS is also induced with a 5 mm x 10 mm microfluidic device manufactured using industry-standard semiconductor processes. Cumulatively, this means μVS is an extremely scalable, gentle, and robust alternative to incumbent technologies, such as viral transduction and electroporation.

...

As of May 2018, Indee Labs had accumulated more than USD$6.1 million dollars in angel, venture, and non-dilutive capital.

Timeline

February 1, 2018

Indee Labs presents at MF-9, the Ninth Microfluidics Consortium.

Indee Labs presents at MF-9, the Ninth Microfluidics Consortium.

January 24, 2018

Indee Labs is featured by Main Sequence Ventures

January 8, 2018

Indee Labs is mentioned by the Australian Trade and Investment CommissionCom.

Indee Labs mentioned by the Australian Trade and Investment Commission.

December 7, 2017

Indee Labs is selected for the Wilson Sonsini Goodrich & Rosati Healthcare Innovations Venture Investment Forum.

Indee Labs selected for the Wilson Sonsini Goodrich & Rosati Healthcare Innovations Venture Investment Forum.

November 15, 2017

Indee Labs is featured by Eagar & Martin Patent & Trademark Attorneys.

Indee Labs featured by Eagar & Martin Patent & Trademark Attorneys.

October 4, 2017

Lightning Talk at Synbiobeta

Amy Twite presents a Lightning Talk at Synbiobeta.

October 4, 2017

Amy Twite presents a Lightning Talk at Synbiobeta.

July 3, 2017

Indee Labs closes $1.3M Angel Round.

Indee Labs closes $1.3M Angel Round.

May 24, 2017

Indee Labs selected to present at Australian-American Enabling Technologies Meeting.

Indee Labs selected to present at Australian-American Enabling Technologies Meeting.

March 20, 2017

Indee Labs launches at Y Combinator’s Winter 2017 Demo Day.

Indee Labs launches at Y Combinator’s Winter 2017 Demo Day.

Edits on 3 Nov, 2022
Ivan Avdeev
Ivan Avdeev edited on 3 Nov, 2022
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Founded date
August 2015
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Email address
hello@indeelabs.com
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Company Operating Status
Active
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Edits on 7 Jun, 2022
Duzenko Andrey
Duzenko Andrey edited on 7 Jun, 2022
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Company Operating Status
Active
Email address
hello@indeelabs.com
Founded date
August 2015
Full address
626 Bancroft Way Suite A Berkeley, CA 94710 United States
Key people
Place of incorporation
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Number of employees
300
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Lily Colman

Operations Associate

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Elisey Ruban edited on 16 Mar, 2022
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