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HotSpot Therapeutics

HotSpot Therapeutics

Biotechnology company developing medicines that target allosteric regulatory sites on proteins

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Edits on 12 May, 2021
Golden AI"Funding autocalculation"
Golden AI edited on 12 May, 2021
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Latest funding type
Series A round
Edits on 24 Apr, 2021
Neelam Jhaveri
Neelam Jhaveri edited on 24 Apr, 2021
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HotSpot Therapeutics

Biotechnology company developing medicines that target allosteric regulatory sites on proteins

Timeline

April 14, 2021

HotSpot Therapeutics announces the appointment of industry leader, Timothy Reilly, as Chief Development Officer.
Edits on 29 Mar, 2021
Golden AI"Found on funding round"
Golden AI edited on 29 Mar, 2021
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Investors
Edits on 5 Feb, 2021
Henry Ogolla
Henry Ogolla approved a suggestion from Golden's AI on 5 Feb, 2021
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Article

HotSpot Therapeutics target regulatory mechanisms to create allosteric medicines such as small molecule molecules for treatment of autoimmune and rare diseases as well as cancer. The company’s SpotFinder technology platform is used to identify and target regulatory hotspots, a unique family of pockets situated remotely from the active site on a protein that are normally used in the body to control protein function. HotSpot’s lead compounds include allosteric inhibitors targeting PKC-theta for autoimmune diseasesautoimmune diseases and S6 kinase involved in mitochondrial and metabolic function.

Edits on 1 Feb, 2021
Golden AI"prospector:137:67691"
Golden AI edited on 1 Feb, 2021
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Edits on 31 Jan, 2021
Meredith Hanel
Meredith Hanel edited on 31 Jan, 2021
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Article (+581 characters)
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HotSpot Therapeutics

Biotechnology company developing medicines that target allosteric regulatory sites on proteins

Article

HotSpot Therapeutics target regulatory mechanisms to create allosteric medicines such as small molecule molecules for treatment of autoimmune and rare diseases as well as cancer. The company’s SpotFinder technology platform is used to identify and target regulatory hotspots, a unique family of pockets situated remotely from the active site on a protein that are normally used in the body to control protein function. HotSpot’s lead compounds include allosteric inhibitors targeting PKC-theta for autoimmune diseases and S6 kinase involved in mitochondrial and metabolic function.

Edits on 6 Oct, 2020
Golden AI"Funding autocalculation"
Golden AI edited on 6 Oct, 2020
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Infobox (+1 properties)
Infobox
Latest funding round date
July 17, 2018
Edits on 25 Sep, 2020
Golden AI"Funding autocalculation"
Golden AI edited on 25 Sep, 2020
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Infobox
Total funding amount (USD)
45,000,000
Golden AI
Golden AI edited on 25 Sep, 2020
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Edits on 20 Jun, 2020
Henry Ogolla
Henry Ogolla edited on 20 Jun, 2020
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Timeline

May 21, 2020

HotSpot Therapeutics raises a $65 million series B to fund development of allosteric medicines.
Edits on 8 Jul, 2019
Golden AI"Remove default description"
Golden AI edited on 8 Jul, 2019
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HotSpot Therapeutics

Company

Edits on 26 Apr, 2019
Julius John Villarisco"Approved suggestion from source: http://www.hotspotthera.com/"
Julius John Villarisco approved a suggestion from Golden's AI on 26 Apr, 2019
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Edits on 17 Apr, 2019
Golden AI
Golden AI edited on 17 Apr, 2019
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HotSpot Therapeutics

Company

Edits on 7 Mar, 2019
Golden AI
Golden AI edited on 7 Mar, 2019
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Edits on 5 Mar, 2019
Rebecca Hammond
Rebecca Hammond approved a suggestion from Golden's AI on 5 Mar, 2019
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Rebecca Hammond"Initial topic creation"
Rebecca Hammond created this topic on 5 Mar, 2019
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 HotSpot Therapeutics

Biotechnology company developing medicines that target allosteric regulatory sites on proteins

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