Epigenetic CRISPR/Cas9

Epigenetic CRISPR/Cas9

Epigenetic CRISPR/Cas9 is a modified form of the gene editing technology CRISPR, designed to modify the epigenome, rather than the genome. Without cutting DNA the system activates or represses genes.

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Rachel Phythian"New topic"
Rachel Phythian edited on 14 Dec, 2017
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Epigenetic CRISPR/Cas9

Gene editing technology

Article

Epigenetic CRISPR/Cas9 is a modified form of the gene editing technology CRISPR, designed to activate genes without cutting DNA.

Academic papers

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Hsin-Kai Liao7, Fumiyuki Hatanaka7, Toshikazu Araoka7, Pradeep Reddy, Min-Zu Wu, Yinghui Sui, Takayoshi Yamauchi, Masahiro Sakurai, David D. O’Keefe, Estrella Núñez-Delicado, Pedro Guillen, Josep M. Campistol, Cheng-Jang Wu, Li-Fan Lu, Concepcion Rodriguez Esteban, Juan Carlos Izpisua Belmonte

In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation

http://www.cell.com/cell/abstract/S0092-8674(17)31247-3

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