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EpiBone

EpiBone

EpiBone is a biotechnology startup company developing bone reconstruction solutions using stem cells. Nina Tandon, Sarindr Bhumiratana, Gordana Vunjak-Novakovic, and Sidney Eisig founded EpiBone in 2013 and the company is headquartered in New York City, New York.

EpiBone is a biotechnology company headquartered in New York City, New York that was founded in 2013 by Nina Tandon, Sarindr Bhumiratana, Gordana Vunjak-Novakovic, and Sidney Eisig. CEO and Co-Founder Nina Tandon worked on heart regeneration for her PhD, worked at McKinsey management consultancy and has an MBA. 



EpiBone uses a biomedical engineering process that includes 3D printing to create individualized bone grafts using a patients own mesenchymal stem cells grown in the company's custom built bioreactor. The process involves a CT scan to determine the exact size and shape of a needed bone. A precise, personalized scaffold is created. The patient’s stem cells are cultured so that they start becoming bone cells and are placed on the scaffold and remodel into a personalized bone graft that can be implanted.



Pipeline

Phase 1 and 2 clinical trial Investigational New Drug (IND) clearance was granted by the FDA in 2019 for their product EpiBone-Craniomaxillofacial (EB-CMF) as a treatment for ramus continuity defects in the mandible. The product is anatomically correct and manufactured from a patient’s own adipose derived stem cells.



Funding

Grant

On June 12, 2014 EpiBone received an undisclosed amount of funding in the form of a grant from the Partnership Fund for New York City and Breakout Labs. 

Convertible Note

On October 1, 2016 EpiBone received a convertible note worth $560 thousand from Plum Alley. 



Timeline

May 22, 2019

EpiBone, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted its Investigational New Drug (IND) clearance to proceed with a Phase 1/2 clinical trial of its lead bone product EpiBone-Craniomaxillofacial (EB-CMF), as a potential treatment for ramus continuity defects in the mandible.

People

Name
Role
LinkedIn

Cato Laurencin

Advisor



Cliff Schorer

Advisor



Elma Hawkins

Chairman



Gordana Vunjak-Novakovic

Co-Founder & Chief Scientific Advisor



Hank Kucheman

Advisor



Henry Kravis

Advisor



Nina Tando

Co-Founder & CEO



Sarindr Bhumiratana

Co-Founder & CEO



Sidney Eisig

Co-Founder & Chief Clinical Advisor



Further reading

Title
Author
Link
Type
Date

How a Bone-Growing Startup Lured 66 Investors, Including Peter Thiel

Liz Welch

Web



Why Peter Thiel Invested In New York Biotech Startup EpiBone

Liz Welch

News



Documentaries, videos and podcasts

Title
Date
Link

Nina Tandon CEO and Co Founder EpiBone

May 17, 2018

Nina Tandon: Could tissue engineering mean personalized medicine?

December 6, 2018

Companies

Company
CEO
Location
Products/Services









References