Drug discovery

Drug discovery

The process by which new candidate medications are discovered

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Dawson Sewell
Dawson Sewell edited on 8 Oct, 2020
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Selecting a clinical candidate

Selecting a clinical candidate


Clustered regularly interspaced short palindromic repeats (CRISPR)

Clustered regularly interspaced short palindromic repeats (CRISPR) technology gives drug discovery researchers the ability to alter sequences and expression levels of genes to help them identify therapeutic drug targets and test the therapeutic efficiency of drug candidates. CRISPR has become more useful in the drug discovery process as the cost of using CRISPR and DNA sequencing technologies has decreased due to technological and economies of scale improvements. CRISPR can play a role in several stages of the drug discovery process as outlined in the following diagram:

Role of CRISPR in the stages of Drug Discovery.
Further reading


How CRISPR Is Accelerating Drug Discovery

Brittany L. Enzmann, PhD, Ania Wronski, PhD


January 11, 2019

How CRISPR is transforming drug discovery

Andrew Scott


March 7, 2018

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