Cluster: Microbiome and gut health

Cluster: Microbiome and gut health

A cluster of topics related to microbiome and gut health.

All edits by  Meredith Hanel 

Edits on 17 Feb, 2020
Meredith Hanel
Meredith Hanel edited on 17 Feb, 2020
Edits made to:
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  • 16s sequencing of 16S rRNA. The highly conserved region of the genome that codes for 16S ribosomal RNA in bacteria and archaea is amplified by PCR and sequenced. Specific sequence differences correspond to a taxa at an operational taxonomic unit (OTU). OTUs correspond to organisms at the phyla and genera level and can be less precise at the species level.
  • 18s sequencing of 18S rRNA. . SimilarUsed for eukaryotes, homologous to the 16S rRNA region used for bacterial and archaea.
Meredith Hanel
Meredith Hanel edited on 17 Feb, 2020
Edits made to:
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  • 18s sequencing of 18S rRNA. Similar to 16S rRNA region used for bacterial and archaea.
Edits on 17 Feb, 2020
Meredith Hanel
Meredith Hanel edited on 17 Feb, 2020
Edits made to:
Article (+37/-19 characters)
Article

NGS platforms sequence millions of small DNA fragments in parallel. Bioinformatics uses sequence maps to figure out where the sequenced fragments fit. NGS can sequence entire genomes or target specific regions. Amplicon sequencingAmplicon sequencing targets specific regions by PCR which are then sequenced with NGS.

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  • 16s sequencing of 16S rRNA. The highly conserved region of the genome that codes for 16S ribosomal RNA in bacteria and archaea is amplified by PCR and sequenced. Specific sequence differences correspond to a taxa at an operational taxonomic unit (OTU). OTUs correspond to organisms at the phyla and genera level and can be less precise at the species level.
Edits on 26 Nov, 2019
Meredith Hanel
Meredith Hanel edited on 26 Nov, 2019
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  • Pando Nutrition
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  • Pando Nutrition
Edits on 1 Nov, 2019
Meredith Hanel
Meredith Hanel edited on 1 Nov, 2019
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  • MALDI-TOF mass spectrometry. Matrix assisted laser desorption ionization (MALDI) is a form of mass spectrometry that is used to generate a protein mass fingerprint (PMF) which is compared to a database. Mass spectrometry is a technique that uses ionization to categorize chemical compounds based on their mass to charge ratio. Microbial applications usually use time of flight (TOF) analyzers to measure mass.
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Edits on 13 Sep, 2019
Meredith Hanel
Meredith Hanel edited on 13 Sep, 2019
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Edits on 11 Sep, 2019
Meredith Hanel
Meredith Hanel edited on 11 Sep, 2019
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Edits on 7 Sep, 2019
Meredith Hanel
Meredith Hanel edited on 7 Sep, 2019
Edits made to:
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Gut bacteria associated with health conditions
Health conditions associated with altered gut bacteria
  • Crohn's disease
  • Ulcerative colitis
Edits on 3 Sep, 2019
Meredith Hanel
Meredith Hanel edited on 3 Sep, 2019
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Healthcare
Health and disease companies
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Agriculture Companies
Meredith Hanel
Meredith Hanel edited on 3 Sep, 2019
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Probiotics are a live microbe. Some probiotics are classified as medical foodsmedical foods.

Edits on 7 May, 2019
Meredith Hanel
Meredith Hanel edited on 7 May, 2019
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Gut bacteria associated with health conditions
  • Parasporobacterium - Irritable Bowel Syndrome, Down Syndrome
Edits on 28 Apr, 2019
Meredith Hanel
Meredith Hanel edited on 28 Apr, 2019
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  • The gut phageome is the community of phage viruses associated with the gut microbiome
Edits on 11 Apr, 2019
Meredith Hanel
Meredith Hanel edited on 11 Apr, 2019
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Microbiome bioinformatics
  • Juno Bio
Edits on 20 Mar, 2019
Meredith Hanel
Meredith Hanel edited on 20 Mar, 2019
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Probiotics are a live microbe. Some probiotics are classified as medical foods.

  • VSL 3 Probiotic
  • VSL#3 Probiotic distributed by Sigma-Tau Healthscience USA and VSL Pharmaceuticals
Edits on 13 Mar, 2019
Meredith Hanel
Meredith Hanel edited on 13 Mar, 2019
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Edits on 8 Feb, 2019
Meredith Hanel
Meredith Hanel edited on 8 Feb, 2019
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  • Mother Dirt
Edits on 21 Jan, 2019
Meredith Hanel
Meredith Hanel edited on 21 Jan, 2019
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The use of bacteriophages or phages therapeutically as antimicrobial treatments against bacteria.

Meredith Hanel
Meredith Hanel edited on 21 Jan, 2019
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Phage Therapy
  • Locus Biosciences
  • Eligo Bioscience
  • Nextbiotics
  • Nestle
  • BiomX
  • PhagoMed
  • Pherecydes Pharma
Edits on 14 Jan, 2019
Meredith Hanel
Meredith Hanel edited on 14 Jan, 2019
Edits made to:
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  • Eligo Bioscience
Edits on 14 Jan, 2019
Meredith Hanel
Meredith Hanel edited on 14 Jan, 2019
Edits made to:
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Bacteria, including archae, yeast, fungi, viruses are all found in the human gut.

  • Many commensal and pathogenic gut bacteria possess invertons which help them colonize and/or contribute to persistance of antibiotic resistance
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