Cluster: COVID-19

Cluster: COVID-19

A cluster of topics related to COVID-19. COVID-19 is the abbreviated name for coronavirus disease 2019, a respiratory disease caused by a novel coronavirus strain called SARS-CoV-2. COVID-19 was first detected in Wuhan City, China and the outbreak was declared a pandemic on March 11, 2020 by the WHO.

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Edits on 14 Oct, 2020
Henry Ogolla
Henry Ogolla approved a suggestion from Golden's AI on 14 Oct, 2020
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COVID-19 diagnostic testing is performed on sputum, nose, and throat swabs. In early March 2020, governments restricted COVID-19 testing to central health agencies or a few accredited laboratories for a real-time reverse-transcription PCR (RT-PCR)-based protocol selected by the WHO. Reverse transcription means a reverse transcriptase enzyme is used to convert RNA template to cDNA before PCR amplification which produces a large number of copies of the cDNA. Real-time PCR is sometimes called quantitative PCR (qPCR or qRT-PCR). Tests that use PCR are also referred to as nucleic acidnucleic acid amplification tests (NAAT) as they amplify deoxyribonucleic acid (DNA). The COVID-19 real-time RT-PCR test detects the presence of the E gene of SARS-CoV-2, coding for the envelope surrounding the viral shell and the gene for the enzyme RNA-dependent RNA polymerase. Once samples are received in a laboratory, it takes 24-48 hours for results. The tests were confirmed to be accurate with whole genome sequencing. The US Centers for Disease Control and Prevention (CDC) has an RT-PCR assay that includes primers for the nucleocapsid phosphoprotein in the virus shell and for the RNA-dependent RNA polymerase gene. In the UK, COVID-19 testing is done by accredited laboratories. In the US COVID-19 testing was initially done exclusively by the CDC which later began sending out RT-PCR test kits to state health laboratories. Some clinical tests on sale in the US were made available under CLIA waivers, which regulate the facility where the tests are conducted, rather than the tests themselves. The FDA announced on February 29 that CLIA-certified labs do not need to obtain emergency use authorization (EUA).

Edits on 6 Sep, 2020
Henry Ogolla
Henry Ogolla approved a suggestion from Golden's AI on 6 Sep, 2020
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The vaccine called Ad5-nCoV that was developed by the Beijing Institute of Biotechnology and the company CanSino Biologics was approved by the Chinese government for use for military personnel on June 25, 2020. The vaccine is being tested in clinical trials in China and in Canada in a collaboration between CanSino Biolgics and the National Research Council of Canada (NRC). In the vaccine development, a proprietary HEK293 cell line of the NRC and part of the work of Dr. Frank Graham (McMaster UniversityMcMaster University, Canada).

Henry Ogolla
Henry Ogolla approved a suggestion from Golden's AI on 5 Sep, 2020
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In China an experimental COVID-19 vaccine was approved for use in individuals working in high risk professions on July 22, 2020. The vaccine was developed by Sinopharm’s China National Biotec Group Company (CNBG). At the time the vaccine had completed Phase 3 clinical trials in UAE, Peru, MoroccoMorocco and Argentina.

Henry Ogolla
Henry Ogolla approved a suggestion from Golden's AI on 5 Sep, 2020
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In China an experimental COVID-19 vaccine was approved for use in individuals working in high risk professions on July 22, 2020. The vaccine was developed by Sinopharm’s China National Biotec Group Company (CNBG). At the time the vaccine had completed Phase 3 clinical trials in UAE, PeruPeru, Morocco and Argentina.

Henry Ogolla
Henry Ogolla approved a suggestion from Golden's AI on 5 Sep, 2020
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In China an experimental COVID-19 vaccine was approved for use in individuals working in high risk professions on July 22, 2020. The vaccine was developed by Sinopharm’s China National Biotec Group Company (CNBG). At the time the vaccine had completed Phase 3 clinical trials in UAE, Peru, Morocco and ArgentinaArgentina.

Henry Ogolla
Henry Ogolla approved a suggestion from Golden's AI on 5 Sep, 2020
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The Russian Ministry of Health issued a registration certificate on August 11, 2020 for a COVID-19 vaccine developed by the Gamaleya Research Institute of Epidemiology and Microbiology in Moscow, that had been tested in 76 people. The vaccine was dubbed Sputnik V. The certificate allows the vaccine to be given to a small number of citizens from vulnerable groups such as medical staff and the elderly. The certificate is similar to the FDA granting emergency use authorization. It is stipulated in the certificate that the vaccine cannot be widely used until January 1, 2021. It is expected that at this time larger clinical trials will have been completed. The certification of the vaccine received criticism for being premature and potentially exposing those who receive the vaccine to unnecessary risk. The vaccine is manufactured by Binnopharm in ZelenogradZelenograd. The vaccine uses an adenovirus carrier engineered to carry the spike protein of SARS-CoV-2.

Edits on 5 Sep, 2020
Henry Ogolla
Henry Ogolla approved a suggestion from Golden's AI on 5 Sep, 2020
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Gamaleya Research Institute of Epidemiology and Microbiology (RussiaRussia)

Henry Ogolla
Henry Ogolla approved a suggestion from Golden's AI on 5 Sep, 2020
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Gamaleya Research Institute of Epidemiology and MicrobiologyMicrobiology (Russia)

Edits on 2 Sep, 2020
Henry Ogolla
Henry Ogolla approved a suggestion from Golden's AI on 2 Sep, 2020
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OWS funded Janssen, Moderna and AstraZeneca, Novavax, Pfizer, Sanofi and GlaxoSmithKlineGlaxoSmithKline supporting COVID-19 vaccine development and large-scale manufacturing. OWS funded Regeneron supporting their COVID-19 anti-viral antibody treatment. Task orders with Emergent BioSolutions and Texas A&M University and FUJIFILM are aimed to advance US manufacturing capabilities. Grand River Aseptic Manufacturing (GRAM) in Michigan, USA received a contract with OWS for fill and finish manufacturing of critical vaccines and therapeutics.

Henry Ogolla
Henry Ogolla approved a suggestion from Golden's AI on 2 Sep, 2020
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OWS funded Janssen, Moderna and AstraZeneca, Novavax, Pfizer, Sanofi and GlaxoSmithKline supporting COVID-19 vaccine development and large-scale manufacturing. OWS funded Regeneron supporting their COVID-19 anti-viral antibody treatment. Task orders with Emergent BioSolutionsEmergent BioSolutions and Texas A&M University and FUJIFILM are aimed to advance US manufacturing capabilities. Grand River Aseptic Manufacturing (GRAM) in Michigan, USA received a contract with OWS for fill and finish manufacturing of critical vaccines and therapeutics.

Henry Ogolla
Henry Ogolla approved a suggestion from Golden's AI on 2 Sep, 2020
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In Canada vaccine production may take place at the Human Health Therapeutics Research Centre in MontrealMontreal. The Canadian government has signed deals with Moderna, Pfizer/BioNTech, Novavax and Janssen to reserve millions of doses of COVID-19 vaccine.

Henry Ogolla
Henry Ogolla approved a suggestion from Golden's AI on 2 Sep, 2020
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OWS funded Janssen, Moderna and AstraZenecaAstraZeneca, Novavax, Pfizer, Sanofi and GlaxoSmithKline supporting COVID-19 vaccine development and large-scale manufacturing. OWS funded Regeneron supporting their COVID-19 anti-viral antibody treatment. Task orders with Emergent BioSolutions and Texas A&M University and FUJIFILM are aimed to advance US manufacturing capabilities. Grand River Aseptic Manufacturing (GRAM) in Michigan, USA received a contract with OWS for fill and finish manufacturing of critical vaccines and therapeutics.

Edits on 7 Mar, 2020
Henry Ogolla
Henry Ogolla approved a suggestion from Golden's AI on 7 Mar, 2020
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XAG is an agricultural technology company whose agricultural robots and drones have been adapted for testing scenarios to spray disinfectant to reduce the spread of COVID-19 and have been deployed in GuangzhouGuangzhou. High concentrated disinfectants can be sprayed from drone nozzles or robot jet sprayers and diluted with moisture in the air and potential targets include hospitals and schools.

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