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Circle Pharma

Circle Pharma

Biotechnology company developing cell permeable macrocyclic peptide therapeutics using an automated chemistry synthesis.

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Edits on 28 Mar, 2021
Golden AI"Found on funding round"
Golden AI edited on 28 Mar, 2021
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Investors
Mission Bay Capital
Edits on 6 Oct, 2020
Golden AI"Funding autocalculation"
Golden AI edited on 6 Oct, 2020
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Latest funding round date
March 17, 2020
Edits on 25 Sep, 2020
Golden AI"Funding autocalculation"
Golden AI edited on 25 Sep, 2020
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Total funding amount (USD)
49,500,000
Golden AI
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Golden AI
Golden AI edited on 25 Sep, 2020
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Edits on 5 Jun, 2020
Golden AI
Golden AI edited on 5 Jun, 2020
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Investors
Edits on 15 Nov, 2019
Meredith Hanel
Meredith Hanel edited on 15 Nov, 2019
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People (+4 rows) (+8 cells) (+175 characters)
Further reading (+2 rows) (+8 cells) (+332 characters)
People

Name
Role
LinkedIn

David C. Spellmeyer, PhD

Interim Chief Scientific Officer

David J. Earp, J.D., Ph.D.

President, CEO

Matthew P. Jacobson, Ph.D.

Co-Founder, SAB Member

R. Scott Lokey, Ph.D.

Co-Founder

Further reading

Title
Author
Link
Type
Date

Discovery of Potent and Orally Bioavailable Macrocyclic Peptide-Peptoid Hybrid CXCR7 Modulators. - PubMed - NCBI

pubmeddev, Boehm M , et al.

Web

Peptide Therapeutics Near the Sweetest Spots

Web

March 29, 2018

Timeline

January 17, 2018

Circle Pharma Announces Publication in Journal of Medicinal Chemistry of Results from Collaboration with Pfizer Inc.

Circle Pharma, Inc. today announced that results from its collaborative work with Pfizer Inc. to develop a potent and orally bioavailable macrocycle modulator of the chemokine receptor, CXCR7, have been published in the Journal of Medicinal Chemistry.

April 25, 2017

Circle Pharma Announces Expansion of Series A Financing and Appointment of James C. Lu to Its Board

Circle Pharma, Inc. today announced that it has completed an expansion of its Series A financing, with new investors WI Harper Group, Elements Partners, LLC, Whitesun Healthcare Ventures Limited and LifeForce Capital joining the round.

Edits on 13 Nov, 2019
Meredith Hanel
Meredith Hanel edited on 13 Nov, 2019
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Article (+809 characters)
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Topic thumbnail

Circle Pharma

Biotechnology company

Biotechnology company developing cell permeable macrocyclic peptide therapeutics using an automated chemistry synthesis.

Article

Circle Pharma operates an indication-agnostic discovery engine for the development of cell permeable macrocyclic peptide therapeutics. Computational structure-based design is combined with automated, fully synthetic chemistry. In the computational design workflow, large virtual libraries of diverse macrocycles for intrinsic cell permeability and target affinity are generated and screened. Circle Pharma’s technology allows them to target intracellular targets such as protein-protein interactions and achieve oral bioavailability. The automated chemistry synthesis is used to assess in parallel multiple design hypotheses for a given target and rapidly explore structure activity relationships. Circle Pharma is initially focused on intracellular protein-protein interactions that drive oncology pathways.

Categories
Edits on 24 Sep, 2019
Golden AI"Set entity company status to Active"
Golden AI edited on 24 Sep, 2019
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Company status
Active
Edits on 14 Apr, 2019
Henry Ogolla"Approved suggestion from source: http://circlepharma.com/"
Henry Ogolla approved a suggestion from Golden's AI on 14 Apr, 2019
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Edits on 2 Apr, 2019
Carla Faraguna"Approved suggestion from source: http://circlepharma.com/"
Carla Faraguna approved a suggestion from Golden's AI on 2 Apr, 2019
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Circle Pharma

Biotechnology company developing cell permeable macrocyclic peptide therapeutics using an automated chemistry synthesis.

Edits on 7 Mar, 2019
Golden AI
Golden AI edited on 7 Mar, 2019
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Edits on 5 Mar, 2019
Henry Ogolla
Henry Ogolla approved a suggestion from Golden's AI on 5 Mar, 2019
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Edits on 30 May, 2018
Jude Gomila
Jude Gomila edited on 30 May, 2018
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Circle Pharma

Biotechnology companiescompany

Jude Gomila
Jude Gomila edited on 30 May, 2018
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Circle Pharma

Biotechnology companies

Jude Gomila"Initial topic creation"
Jude Gomila created this topic on 30 May, 2018
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 Circle Pharma

Biotechnology company developing cell permeable macrocyclic peptide therapeutics using an automated chemistry synthesis.

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