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Chronomics

Chronomics

Chronomics is an AI-driven platform company that tracks epigenetics for personalized healthcare based in the United Kingdom.

Chronomics provides a test that combines Epigenome Sequencing with Machine Learning. The company provides actionable epigenetic insights. Chronomics is focused on health, wellbeing and prevention of age and lifestyle related diseases by monitoring and reducing risk factors. 



While DNA sequence is fixed from birth, environmental factors and lifestyle can trigger epigenetic changes. Chronomics analyses the epigenetic mark called DNA methylation which is a methyl group added to DNA. DNA methylation mostly occurs on cytosine bases where cytosine is followed by a guanine base (CpG site). There are more than 28 million CpG sites in the human genome and the methylation readout is a binary variable. Each site is methylated or not methylated and the methylation state is influenced by genetics, the environment and health. 



Chronomics uses saliva, which contains buccal epithelial cells and leukocytes, for DNA methylation profiling. Saliva DNA methylation profiles are correlated with those in blood and brain, so saliva can be used to capture effects associated with many complex traits. Users are also asked to fill out a lifestyle questionnaire. To interpret their results, users share their data with Chronomics' team of healthcare professionals, to help provide personalised recommendations to become healthier. Users can test annually to look for health improvements over time.



As of November 2019, Chronomics is serving private healthcare, practitioners and preventive healthcare programs in major health systems, and has stated that they plan to enter into pharmaceutical, biotechnology, and insurance.

Timeline

January 11, 2019

Chronomics secured £1.12million in seed funding. The Cambridge start-up got the backing of venture investment firm Anthemis and follow-on funding from early-stage biotech investor SOSV.

People

Name
Role
LinkedIn

Charles Ball

Co-founder/COO

Dr. Toby Call

Co-founder/CBDO

Sana Wahid

Head of Operations

Further reading

Title
Author
Link
Type
Date

Chronomics secures seed funding, policymakers urged to put tech talent "at the top of the agenda", and more EU news in brief



Web

January 16, 2019

cuRRBS: simple and robust evaluation of enzyme combinations for reduced representation approaches. - PubMed - NCBI

pubmeddev, Martin-Herranz DE , et al.

Journal



DNA test predicts everything from longevity to whether you'll get heart disease or cancer

By Jonathan Gornall For The Daily Mail

Web

July 15, 2019

Epigenetic testing firms claim to help you live a healthier lifestyle

Graham Lawton

Web



Meet the Startup: Chronomics' epigenetics out of the lab - Longevity.Technology



Web

November 12, 2019

Multi-tissue DNA methylation age predictor in mouse. - PubMed - NCBI

pubmeddev, Stubbs TM , et al.

Journal



Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1

Daniel E. Martin-Herranz, Erfan Aref-Eshghi, Marc Jan Bonder, Thomas M. Stubbs, Sanaa Choufani, Rosanna Weksberg, Oliver Stegle, Bekim Sadikovic, Wolf Reik, Janet M. Thornton

Journal

August 14, 2019

We Are More Than Our DNA

Yiannis Mouratidis

Web

November 17, 2018

Documentaries, videos and podcasts

Title
Date
Link

Ageing Environments and Epigenetics: Dr. Tom Stubbs, CEO of Chronomics

November 18 2018

AXA Health Tech & You Awards | Chronomics

July 2nd 2019

Chronomics pitching on the main stage at Web Summit 2019

November 6th 2019

Dr. Daniel Herranz interviewed at the Biohacker's Summit 2019

November 2nd 2019

Epigenetics With Dr. Tom Stubbs (Biohacker's Live show)

June 24 2019

Frontier Epigenetics with Dr. Tom Stubbs | Decoding Superhuman

January 3rd 2019

Companies

Company
CEO
Location
Products/Services









References