Chloroquine

Chloroquine

Chemical compound and drug used to treat malaria, autoimmune disease and other conditions

All edits by  Neelam Jhaveri 

Edits on 7 April, 2020
Neelam Jhaveri
Neelam Jhaveri approved a suggestion from Golden's AI on 7 April, 2020 3:58 am
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A randomized controlled trial conducted by researchers at Wuhan UniversityWuhan University including 62 patients found that time to clinical recovery, based on clinical characteristics and radiological results 5 days after treatment, was significantly shortened in the hydroxychloroquine group.

Edits on 3 April, 2020
Neelam Jhaveri
Neelam Jhaveri approved a suggestion from Golden's AI on 3 April, 2020 7:12 am
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The first controlled study, a randomized trial comparing patients treated with hydroxychloroquine and a control group with 30 patients performed by researchers at Fudan UniversityFudan University, Shanghai. This study led by LU Hongzhou found no difference between the hydroxychloroquine and control groups in time to achieve negative throat swabs for the virus and normalization of body temperature and radiological progression by CT imaging. The authors noted that a larger sample size was needed to assess the effects of hydroxychloroquine on COVID-19.

Neelam Jhaveri
Neelam Jhaveri approved a suggestion from Golden's AI on 3 April, 2020 6:45 am
Edits made to:
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As of March 26, 2020 the NIH Clinical Trials database showed 18 clinical trials listing hydroxychloroquine as an intervention. Hydroxychloroquine alone and in combination with the the antibiotic azithromycin (aka Zithromas or Azithrocin) have reported early evidence of being effective in treating COVID-19 in preliminary results in a small study on 30 patients in France, led by Didier RaoultDidier Raoult. The trial lacks a control group that did not receive hydroxychloroquine. According to the paper Azithromycin was given to some patients to prevent bacterial super-infection. Azithromycin is also known to have immunomodulatory effects.It is not clear if differences between patients that received hydroxychoroquine alone and the combination therapy may be due to differences in the patient's viral load between the two groups. Subsequent results from Raoult's group have been released where all patients were given hydroxychloroquine and azithromycin.

Edits on 27 March, 2020
Neelam Jhaveri
Neelam Jhaveri approved a suggestion from Golden's AI on 27 March, 2020 7:28 am
Edits made to:
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As of March 26, 2020 the NIH Clinical Trials database showed 18 clinical trials listing hydroxychloroquine as an intervention. Hydroxychloroquine alone and in combination with the the antibiotic azithromycin (aka Zithromas or Azithrocin) have shown early evidence of being effective in treating COVID-19 in preliminary results in a small study on 30 patients in FranceFrance. Azithromycin was given to some patients to prevent bacterial super-infection. Azithromycin is also known to have immunomodulatory effects.It is not clear if differences between patients that received hydroxychoroquine alone and the combination therapy may be due to differences in the patient's viral load between the two groups.

Edits on 19 March, 2020
Neelam Jhaveri
Neelam Jhaveri approved a suggestion from Golden's AI on 19 March, 2020 7:33 am
Edits made to:
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Chloroquine has been reported to be an effective antiviral therapeutic against COVID-19 in treatments done in China and South KoreaSouth Korea, with clinical trial ongoing as of March 2020. Treatment with chloroquine tablets was reported to show favorable outcomes such as faster time to recover and shorter hospital stay in people with COVID-19 infections. Laboratory research from the US CDC shows chloroquine also has potential to treat prophylactically. Chloroquine is being investigated to treat COVID-19 in the form of chloroquine phosphate or hydroxychloroquine sulfate which are sometimes referred to as chloroquine and hydroxychloroquine respectively.

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