Chimeric antigen receptor
A lab engineered receptor designed to bind certain proteins, such as surface proteins on cancer cells, that is added to immune cells for immunotherapy strategies such as directing T cells to fight cancer.
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Allogeneic or universal cell therapy products, also called off-the-shelf cell therapy products would allow a broader implementation of these cell therapies. One method being researched is to derive natural killer (NK) cells from induced pluripotent stem cells (iPS) cells and engineer iPS cell-derived NK cells to target and kill cancer cellcancer cell similarly to CAR-T cells.
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