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Channelrhodopsin

Channelrhodopsin

Channelrhodopsins are light-sensitive receptors naturally found in certain algae. They are notable in the field of optogenetics because the transfection of channelrhodopsins into neurons allows the neurons to be depolarized using blue light.

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Edits on 7 Jul, 2020
Meredith Hanel
Meredith Hanel edited on 7 Jul, 2020
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The video below demonstrates the use of blue light to stimulate channelrhodopsin-2 (ChR-2), proteinsa thatprotein havefrom beenthe algae Chlamydomonas reinhardtii, artificially expressed in the membranes of neurons in the motor cortex of a live mouse. The experimenter is able to control the mouse's movement optically by using ChR-2 as a light-gated ion channel. Since motor control is lateralized and only one side of the motor cortex has been transfected with ChR-2, the mouse involuntarily walks in a circle when the light is on, and can walk normally when the light is off.

Meredith Hanel
Meredith Hanel edited on 7 Jul, 2020
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The video below demonstrates the use of blue light to stimulate channelrhodopsin-2 (ChR-2) proteins that have been artificially expressed in the membranes of neurons in the motor cortex of a live mouse. The experimenter is able to control the mouse's movement optically by using ChR-2 as a light-gated ion channel. Since motor control is lateralized and only one side of the motor cortex has been transfected with ChR-2, the mouse involuntarily walks in a circle when the light is on, and can walk normally when the light is off.

Edits on 22 May, 2020
Golden AI"Wikidata import from WikidataImport2"
Golden AI edited on 22 May, 2020
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Wikidata entity ID
Q905325
Edits on 26 Jun, 2018
Michael Mangus
Michael Mangus edited on 26 Jun, 2018
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Channelrhodopsin

Channelrhodopsins are light-sensitive receptorsreceptors naturally found in certain algaealgae. They are notable in the field of optogeneticsoptogenetics because the transfectiontransfection of channelrhodopsins into neuronsneurons allows the neurons to be depolarized depolarized using blue light.

Edits on 16 Mar, 2018
Jude Gomila
Jude Gomila edited on 16 Mar, 2018
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The video below demonstrates the use of blue light to stimulate channelrhodopsin-2 (ChR-2) proteins that have been artificially expressed in the membranes of neurons in the motor cortex of a live mouse. The experimenter is able to control the mouse's movement optically by using ChR-2 as a light-gated ion channel. Since motor controlmotor control is lateralized and only one side of the motor cortex has been transfected with ChR-2, the mouse involuntarily walks in a circle when the light is on, and can walk normally when the light is off.

Edits on 16 Mar, 2018
Michael Mangus
Michael Mangus edited on 16 Mar, 2018
Edits made to:
Article (+11/-11 characters)
Article

The video below demonstrates the use of blue light to stimulate channelrhodopsin-2 (ChR-2) proteins that have been artificially expressed in the membranes of neurons in the motor cortex of a live mouse. The experimenter is able to control the mouse's movement optically by using ChR-2 as a light-gated ion channel. Since motor control is lateralized and only one side of the motor cortex has been transfectedtransfected with ChR-2, the mouse involuntarily walks in a circle when the light is on, and can walk normally when the light is off.

Michael Mangus
Michael Mangus edited on 16 Mar, 2018
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Edits on 15 Feb, 2018
Jude Gomila"thumbnail"
Jude Gomila edited on 15 Feb, 2018
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Channelrhodopsin

Channelrhodopsins are light-sensitive receptors naturally found in certain algae. They are notable in the field of optogenetics because the transfection of channelrhodopsins into neurons allows the neurons to be depolarized using blue light.

Michael Mangus
Michael Mangus edited on 15 Feb, 2018
Edits made to:
Article (+12/-12 characters)
Article

The video below demonstrates the use of blue light to stimulate channelrhodopsin-2 (ChR-2) proteins that have been artificially expressed in the membranes of neurons in the motor cortexmotor cortex of a live mouse. The experimenter is able to control the mouse's movement optically by using ChR-2 as a light-gated ion channel. Since motor control is lateralized and only one side of the motor cortex has been transfected with ChR-2, the mouse involuntarily walks in a circle when the light is on, and can walk normally when the light is off.

Edits on 15 Feb, 2018
Michael Mangus
Michael Mangus edited on 15 Feb, 2018
Edits made to:
Article (+78/-36 characters)
Article

The video below demonstrates the use of blue light to stimulate channelrhodopsin-2 (ChR-2) proteins that have been artificially insertedexpressed intoin the membranes of neurons in the motor cortex of a live mouse,. enabling theThe experimenter is able to control the mouse's movement optically by using ChR-2 as a light-gated ion channel. Since motor control is lateralizedlateralized and only one side of the motor cortex has been transfected with ChR-2, the mouse involuntarily walks in a circle when the light is on, and can walk normally when the light is off.

Michael Mangus
Michael Mangus edited on 15 Feb, 2018
Edits made to:
Article (+66 characters)
Article

The video below demonstrates the use of blue light to stimulate channelrhodopsin-2 (ChR-2) proteins that have been artificially inserted into the membranes of neurons in the motor cortex of a live mouse, enabling the experimenter to control the mouse's movement optically. Since motor control is lateralized and only one side of the motor cortex has been transfected with ChR-2, the mouse involuntarily walks in a circle when the light is on, and can walk normally when the light is off.

Michael Mangus
Michael Mangus edited on 15 Feb, 2018
Edits made to:
Article (+167/-5 characters)
Article

ThisThe video below demonstrates the use of blue light to stimulate channelrhodopsin-2 (ChR-2) proteins that have been artificially inserted into the membranes of neurons in the motor cortex of a live mouse, enabling the experimenter to control the mouse's movement optically:. Since motor control is lateralized and only one side of the motor cortex has been transfected with ChR-2, the mouse involuntarily walks in a circle.

Michael Mangus
Michael Mangus edited on 15 Feb, 2018
Edits made to:
Article (+28 characters)
Article

This video demonstrates the use of blue light to stimulate channelrhodopsin-2 proteins that have been artificially inserted into the membranes of neurons in the motor cortex of a live mouse, enabling the experimenter to control the mouse's movement optically:

Michael Mangus
Michael Mangus edited on 15 Feb, 2018
Edits made to:
Article (+41/-2 characters)
Article

This video demonstrates the use of blue light to stimulate channelrhodopsin-2 proteins inthat have been artificially inserted into the motor cortex of a live mouse, enabling the experimenter to control the mouse's movement optically:

Jude Gomila
Jude Gomila edited on 15 Feb, 2018
Edits made to:
Article
Article

Michael Mangus
Michael Mangus edited on 15 Feb, 2018
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Article (+74/-5 characters)
Article

This video demonstrates the use of blue rightlight to stimulate channelrhodopsin-2 proteins in the motor cortex of a live mouse, enabling the experimenter to control the mouse's movement optically:

Michael Mangus
Michael Mangus edited on 15 Feb, 2018
Edits made to:
Article (+1 videos) (+124 characters)
Article

This video demonstrates the use of blue right to stimulate channelrhodopsin-2 proteins in the motor cortex of a live mouse:

Michael Mangus
Michael Mangus edited on 15 Feb, 2018
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Description (+241/-86 characters)
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Channelrhodopsin

Channelrhodopsins are light-sensitive receptors which act as light-gated ion channels.

Channelrhodopsins are light-sensitive receptors naturally found in certain algae. They are notable in the field of optogenetics because the transfection of channelrhodopsins into neurons allows the neurons to be depolarized using blue light.

Michael Mangus
Michael Mangus edited on 15 Feb, 2018
Edits made to:
Description (+1 characters)
Topic thumbnail

Channelrhodopsin

Channelrhodopsins are light-sensitive receptors which act as light-gated ion channels.

Michael Mangus
Michael Mangus edited on 15 Feb, 2018
Edits made to:
Description (+17/-16 characters)
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Channelrhodopsin

ChannelrhodopsinChannelrhodopsins are light-sensitive receptors which act as light-gated ion channels

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