Golden
CHAIN Biotechnology

CHAIN Biotechnology

CHAIN Biotechnology is a live biotherapeutics company founded in 2014 and based in Nottingham and Marlow, UK. CHAIN works with the Synthetic Biology Research Centre in Nottingham and has built a live biotherapeutic platform based on Clostridia being to deliver bioactive molecules to treat diseases associated with the human gut microbiome.

CHAIN Biotechnology is a biotechnology company using microbial technologies to develop healthcare products that is headquartered in Marlow, United Kingdom and was founded in 2014 by Basil Omar and Edward Green.



CHAIN’s Clostridium Assisted Drug Delivery (CADD) platform is an engineered strain of Clostridium bacteria that functions as a delivery vehicle for therapeutics. Engineered strains are manufactured in the form of spores and taken as tablets. The spores tolerate stomach acid and acid they germinate the colon the cells proliferate and release a bioactive molecule. CHAIN has other products in development aimed at treating infection, inflammation and metabolic disorders. 



CHAIN’s treatment for Ulcerative Colitis and Crohn’s Disease has been completed pre-clnical testing. Scaling up the manufacturing of the Clostridial spore-based medicines following good manufacturing practice (GMP) will be aided by Porton Biopharma and Scitech. Other products in development focus on treating infection, inflammation and metabolic disorders. 

Funding

Grant

On September 12, 2017 CHAIN Biotechnology received a grant worth £500,000 from Innovative UK. 

Timeline

People

Name
Role
Related Golden topics

Dr. Edward M. Green

Founder, CEO



Edward Green

Founder



Mr. Basil Omar

Founder, Chief Commercial Officer



Mr. Robert James Rickman

Chairman of Management Board



Further reading

Title
Author
Link
Type

Biotech Focus: Interview with Dr Edward Green, CHAIN Biotechnology - Microbiome Times Magazine

Staff Editor

Web

Documentaries, videos and podcasts

Title
Date
Link

IChemE Awards 2016 Finalist - 'Clostridium for high-value chemical production', CHAIN Biotechnology

October 10, 2016

Companies

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CEO
Location
Products/Services









References