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CHAIN Biotechnology

CHAIN Biotechnology

CHAIN Biotechnology is a live biotherapeutics company founded in 2014 and based in Nottingham and Marlow, UK. CHAIN works with the Synthetic Biology Research Centre in Nottingham and has built a live biotherapeutic platform based on Clostridia being to deliver bioactive molecules to treat diseases associated with the human gut microbiome.

CHAIN’s Clostridium Assisted Drug Delivery (CADD) platform is an engineered strain of Clostridium bacteria that functions as a delivery vehicle for therapeutics. Engineered strains are manufactured in the form of spores and taken as tablets. The spores tolerate stomach acid and acid they germinate the colon the cells proliferate and release a bioactive molecule. CHAIN has other products in development aimed at treating infection, inflammation and metabolic disorders.

CHAIN’s treatment for Ulcerative Colitis and Crohn’s Disease has been completed pre-clnical testing. Scaling up the manufacturing of the Clostridial spore-based medicines following good manufacturing practice (GMP) will be aided by Porton Biopharma and Scitech. Other products in development focus on treating infection, inflammation and metabolic disorders.

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Dr. Edward M. Green

Founder, CEO

Edward Green

Founder

Mr. Basil Omar

Founder, Chief Commercial Officer

Mr. Robert James Rickman

Chairman of Management Board

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